All patients could receive concomitant 600 mg IV/PO q24h
All patients could receive concomitant Aug 3, 2023 · Postmarketing side effects of linezolid reported include: superficial tooth discoloration
Physical incompatibilities resulted when ZYVOX I
600 mg PO/IV q12hr for 10-14 days
‡ Oral dosing using either ZYVOX Tablets or ZYVOX for Oral Suspension [see How Supplied/Storage and Handling (16)]
Generic Name (S): linezolid in dextrose 5% Uses Linezolid is an antibiotic used to treat certain serious bacterial infections
1 2 ZYVOX 3 (linezolid) injection 4 (linezolid) tablets 5 (linezolid) for oral 6 suspension 7 8 9 To reduce the development of drug-resistant bacteria and maintain the effectiveness of
Uses Warnings Before taking Dosage Side effects Interactions What is Zyvox? Zyvox is an oxazolidinone antibiotic that fights bacteria in
If linezolid injection is to be given concomitantly with another drug, each drug should be given separately, in accordance with the recommended
10 mg/kg every 8 hours HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use ZYVOX safely and effectively
14 The 400-mg ‡ Oral dosing using either ZYVOX Tablets or ZYVOX for Oral Suspension [see How Supplied/Storage and Handling (16)]
Injection is supplied in single-use, ready-to-use infusion bags
Measure a dose with the supplied syringe or a dose-measuring device (not a kitchen spoon)
ZYVOX 1200 mg dose via a 1 hour IV infusion, placebo, and a single oral dose of positive control
The pharmacokinetic parameters of linezolid are summarized in Table 9 for the pediatric populations studied and healthy adult subjects after administration of single intravenous doses
Linezolid, an oxazolidinone antibacterial, is active against Gram-positive bacteria including meticillin-resistant Staphylococcus aureus (MRSA), and glycopeptide-resistant enterococci
Dosage Guidelines for
ZYVOX I
3
Linezolid injection is supplied in single-use, ready-to-use container (VisIV™ Container) [see How Supplied/Storage and Handling (16)]
2
Methods of intravenous administration
5 g IV every 6 hours: In inpatient and outpatient settings, five-day antibiotic courses are recommended, after which the Nafcillin or oxacillin 2 g IV q4h; Cefazolin 2g IV q8h; MRSA: see above "Empiric
Linezolid belongs to the family of medicines called antibiotics
Linezolid is a synthetic oxazolidinone with bacteriostatic activity against gram-positive organisms [ 1 ]
There were 79 patients randomized to high-dose